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Its best to play these cards if you have a way to avoid losing the next turn, like Angel's Grace, Platinum Angel, or Lich's Mastery

Not having access to your commander limits the effectiveness of your enchantment payoffs, but you can always just cast valuable Sagas from your hand too

Theres also potential to be had using Agnimazud with Kozmos

Those won't be added until much later, in layer 6, so the original creature keeps those abilities and Deadpool won't get them (but that also means you can give your Deadpool an ability and Deadpool keeps that ability)

When it's tapped one player mills its power, so minimum two

Case 2: Sulfefnir gets Destroyed